Formation of Covalently Bound Protein Adducts from the Cytotoxicant Naphthalene in Nasal Epithelium: Species Comparisons

BACKGROUND: Naphthalene is a volatile hydrocarbon that causes dose-, species-, and cell type–dependent cytotoxicity after acute exposure and hyperplasia/neoplasia after lifetime exposures in rodents. Toxicity depends on metabolic activation, and reactive metabolite binding correlates with tissue and...

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Detalles Bibliográficos
Autores principales: DeStefano-Shields, Christina, Morin, Dexter, Buckpitt, Alan
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866680/
https://www.ncbi.nlm.nih.gov/pubmed/20435546
http://dx.doi.org/10.1289/ehp.0901333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866680/
https://www.ncbi.nlm.nih.gov/pubmed/20435546
http://dx.doi.org/10.1289/ehp.0901333

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