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Formation of Covalently Bound Protein Adducts from the Cytotoxicant Naphthalene in Nasal Epithelium: Species Comparisons

BACKGROUND: Naphthalene is a volatile hydrocarbon that causes dose-, species-, and cell type–dependent cytotoxicity after acute exposure and hyperplasia/neoplasia after lifetime exposures in rodents. Toxicity depends on metabolic activation, and reactive metabolite binding correlates with tissue and...

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Detalles Bibliográficos
Autores principales:	DeStefano-Shields, Christina, Morin, Dexter, Buckpitt, Alan
Formato:	Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866680/ https://www.ncbi.nlm.nih.gov/pubmed/20435546 http://dx.doi.org/10.1289/ehp.0901333

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