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Reciprocal Epigenetic Modification of Histone H2B occurs in Chromatin during Apoptosis in vitro and in vivo

Histone H2B phosphorylation at Serine 14 (phosS14) has been proposed as an epigenetic marker of apoptotic cells whereas acetylation at the adjacent Lysine 15 (acK15) is a property of non-dying cells. We investigated the relationship and the potential regulatory mechanisms between these two epigeneti...

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Detalles Bibliográficos
Autores principales: Ajiro, Kozo, Scoltock, Alyson B., Smith, Lindsay K., Ashasima, Makoto, Cidlowski, John A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866817/
https://www.ncbi.nlm.nih.gov/pubmed/20057502
http://dx.doi.org/10.1038/cdd.2009.199