Antigen affinity discrimination is an intrinsic function of the B cell receptor

Antibody affinity maturation, a hallmark of adaptive immune responses, results from the selection of B cells expressing somatically hypermutated B cell receptors (BCRs) with increased affinity for antigens. Despite the central role of affinity maturation in antibody responses, the molecular mechanis...

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Detalles Bibliográficos
Autores principales: Liu, Wanli, Meckel, Tobias, Tolar, Pavel, Sohn, Hae Won, Pierce, Susan K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867278/
https://www.ncbi.nlm.nih.gov/pubmed/20404102
http://dx.doi.org/10.1084/jem.20092123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867278/
https://www.ncbi.nlm.nih.gov/pubmed/20404102
http://dx.doi.org/10.1084/jem.20092123

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