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Affinity measured by microcluster

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation “translate” BCR affinity for antigen into B cell responsiveness.

Detalles Bibliográficos
Autores principales: Fooksman, David R., Dustin, Michael L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867281/
https://www.ncbi.nlm.nih.gov/pubmed/20439542
http://dx.doi.org/10.1084/jem.20100780