Affinity measured by microcluster

Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation “translate” BCR affinity for antigen into B cell responsiveness.

Detalles Bibliográficos
Autores principales: Fooksman, David R., Dustin, Michael L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867281/
https://www.ncbi.nlm.nih.gov/pubmed/20439542
http://dx.doi.org/10.1084/jem.20100780
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author Fooksman, David R.
Dustin, Michael L.
author_facet Fooksman, David R.
Dustin, Michael L.
author_sort Fooksman, David R.
collection PubMed
description Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation “translate” BCR affinity for antigen into B cell responsiveness.
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spelling pubmed-28672812010-11-10 Affinity measured by microcluster Fooksman, David R. Dustin, Michael L. J Exp Med Commentary Like T cell activation, B cell activation is driven by aggregation of B cell receptors (BCRs) into microclusters. New work suggests that the early dynamics of BCR mobility and microcluster formation “translate” BCR affinity for antigen into B cell responsiveness. The Rockefeller University Press 2010-05-10 /pmc/articles/PMC2867281/ /pubmed/20439542 http://dx.doi.org/10.1084/jem.20100780 Text en © 2010 Fooksman and Dustin This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Fooksman, David R.
Dustin, Michael L.
Affinity measured by microcluster
title Affinity measured by microcluster
title_full Affinity measured by microcluster
title_fullStr Affinity measured by microcluster
title_full_unstemmed Affinity measured by microcluster
title_short Affinity measured by microcluster
title_sort affinity measured by microcluster
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867281/
https://www.ncbi.nlm.nih.gov/pubmed/20439542
http://dx.doi.org/10.1084/jem.20100780
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