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Invariant NKT cells limit activation of autoreactive CD1d-positive B cells

Faulty activation of autoreactive B cells is a hallmark of autoimmune diseases like systemic lupus erythematosus (SLE). An important feature restricting activation of autoreactive B cells is efficient removal of apoptotic material. Mounting evidence also connects a primary defect in invariant natura...

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Detalles Bibliográficos
Autores principales: Wermeling, Fredrik, Lind, Sara M., Jordö, Emilie Domange, Cardell, Susanna L., Karlsson, Mikael C.I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867286/
https://www.ncbi.nlm.nih.gov/pubmed/20439539
http://dx.doi.org/10.1084/jem.20091314