The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

Colitis-associated cancer (CAC) is a major complication of inflammatory bowel diseases. We show that components of the inflammasome are protective during acute and recurring colitis and CAC in the dextran sulfate sodium (DSS) and azoxymethane + DSS models. Mice lacking the inflammasome adaptor prote...

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Detalles Bibliográficos
Autores principales: Allen, Irving C., TeKippe, Erin McElvania, Woodford, Rita-Marie T., Uronis, Joshua M., Holl, Eda K., Rogers, Arlin B., Herfarth, Hans H., Jobin, Christian, Ting, Jenny P.-Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867287/
https://www.ncbi.nlm.nih.gov/pubmed/20385749
http://dx.doi.org/10.1084/jem.20100050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867287/
https://www.ncbi.nlm.nih.gov/pubmed/20385749
http://dx.doi.org/10.1084/jem.20100050

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