Cargando…

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

Colitis-associated cancer (CAC) is a major complication of inflammatory bowel diseases. We show that components of the inflammasome are protective during acute and recurring colitis and CAC in the dextran sulfate sodium (DSS) and azoxymethane + DSS models. Mice lacking the inflammasome adaptor prote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Allen, Irving C., TeKippe, Erin McElvania, Woodford, Rita-Marie T., Uronis, Joshua M., Holl, Eda K., Rogers, Arlin B., Herfarth, Hans H., Jobin, Christian, Ting, Jenny P.-Y.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867287/ https://www.ncbi.nlm.nih.gov/pubmed/20385749 http://dx.doi.org/10.1084/jem.20100050

Ejemplares similares

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells
por: Craven, Robin R., et al.
Publicado: (2009)

Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis
por: Allen, Irving C., et al.
Publicado: (2013)

Correction: Characterization of NLRP12 during the In Vivo Host Immune Response to Klebsiella pneumoniae and Mycobacterium tuberculosis
por: Allen, Irving C., et al.
Publicado: (2013)

Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1
por: McElvania TeKippe, Erin, et al.
Publicado: (2010)

Increased Prevalence of Anellovirus in Pediatric Patients with Fever
por: McElvania TeKippe, Erin, et al.
Publicado: (2012)

C. elegans Germline-Deficient Mutants Respond to Pathogen Infection Using Shared and Distinct Mechanisms
por: TeKippe, Michael, et al.
Publicado: (2010)

Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility
por: Uronis, Joshua M., et al.
Publicado: (2009)

Panels and Syndromic Testing in Clinical Microbiology
por: Dien Bard, Jennifer, et al.
Publicado: (2020)

New Developments in Rapid Diagnostic Testing for Children
por: Gonzalez, Mark D., et al.
Publicado: (2018)

Non-Inflammasome Forming NLRs in Inflammation and Tumorigenesis
por: Allen, Irving Coy
Publicado: (2014)

GATA Transcription Factor Required for Immunity to Bacterial and Fungal Pathogens
por: Kerry, Samantha, et al.
Publicado: (2006)

Oroxylin A inhibits colitis by inactivating NLRP3 inflammasome
por: Zhou, Wei, et al.
Publicado: (2017)

Contradictory Effects of NLRP3 Inflammasome Regulatory Mechanisms in Colitis
por: Wagatsuma, Kohei, et al.
Publicado: (2020)

Inflammasome-Associated Gastric Tumorigenesis Is Independent of the NLRP3 Pattern Recognition Receptor
por: West, Alice J., et al.
Publicado: (2022)

Therapeutic interventions target the NLRP3 inflammasome in ulcerative colitis: Comprehensive study
por: Ali, Fares E.M, et al.
Publicado: (2023)

2152. Detection of Uropathogens Using BD Kiestra™ Total Laboratory Automation with Urine Culture Application
por: Patel, Parul, et al.
Publicado: (2019)

Severe COVID-19: NLRP3 Inflammasome Dysregulated
por: van den Berg, Daan F., et al.
Publicado: (2020)

The NLRP6 inflammasome
por: Zheng, Danping, et al.
Publicado: (2020)

Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome
por: Ruiz, Pedro A, et al.
Publicado: (2017)

1996. Enteric Multiplex PCR Testing: Antimicrobial Stewardship Friend or Foe
por: Ellen Acree, Mary, et al.
Publicado: (2019)

Deoxycholic Acid Triggers NLRP3 Inflammasome Activation and Aggravates DSS-Induced Colitis in Mice
por: Zhao, Shengnan, et al.
Publicado: (2016)

GPA peptide inhibits NLRP3 inflammasome activation to ameliorate colitis through AMPK pathway
por: Deng, Zhao, et al.
Publicado: (2020)

Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome
por: Dai, Guoliang, et al.
Publicado: (2020)

C646 Protects Against DSS-Induced Colitis Model by Targeting NLRP3 Inflammasome
por: Xu, Xueming, et al.
Publicado: (2021)

Microcystin-LR Induces and Aggravates Colitis through NLRP3 Inflammasome-Mediated Pyroptosis in Mice
por: Yang, Yue, et al.
Publicado: (2023)

Microbes and colorectal cancer: is there a relationship?
por: Uronis, J.M., et al.
Publicado: (2009)

NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis
por: Itani, Shigehiro, et al.
Publicado: (2016)

Munronoid I Ameliorates DSS-Induced Mouse Colitis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Via Modulation of NLRP3
por: Ma, Xingyu, et al.
Publicado: (2022)

Inhibiting the NLRP3 Inflammasome
por: El-Sharkawy, Lina Y., et al.
Publicado: (2020)

Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly
por: Ding, Wenwen, et al.
Publicado: (2020)

Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation
por: Lv, Qi, et al.
Publicado: (2021)

Baicalin Ameliorates DSS-Induced Colitis by Protecting Goblet Cells through Activating NLRP6 Inflammasomes
por: Li, Yanan, et al.
Publicado: (2022)

PSMB5 Alleviates Ulcerative Colitis by Inhibiting ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis
por: Han, Liang, et al.
Publicado: (2022)

Ononin alleviates DSS‐induced colitis through inhibiting NLRP3 inflammasome via triggering mitophagy
por: Yu, Ting, et al.
Publicado: (2023)

Research Progress of Mitochondrial Mechanism in NLRP3 Inflammasome Activation and Exercise Regulation of NLRP3 Inflammasome
por: Zhang, Tan, et al.
Publicado: (2021)

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
por: Saresella, Marina, et al.
Publicado: (2016)

The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney
por: Kim, Yang Gyun, et al.
Publicado: (2019)

Nonessential Role for the NLRP1 Inflammasome Complex in a Murine Model of Traumatic Brain Injury
por: Brickler, Thomas, et al.
Publicado: (2016)

809. Modified Laboratory Reporting to Prevent Catheter-Associated Urinary Tract Infections (CAUTIs)
por: Monsalud, Cherie Faith, et al.
Publicado: (2020)

Multicenter Evaluation of Processing and Analysis of College of American Pathologists (CAP) Proficiency Testing Samples by Laboratory Automation
por: Babady, N. Esther, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_37241mu2be4q0qhs0mgh2rpi8m