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Tbx1 regulates Vegfr3 and is required for lymphatic vessel development

Lymphatic dysfunction causes several human diseases, and tumor lymphangiogenesis is implicated in cancer spreading. TBX1 is the major gene for DiGeorge syndrome, which is associated with multiple congenital anomalies. Mutation of Tbx1 in mice recapitulates the human disease phenotype. In this study,...

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Detalles Bibliográficos
Autores principales: Chen, Li, Mupo, Annalisa, Huynh, Tuong, Cioffi, Sara, Woods, Matthew, Jin, Chengliu, McKeehan, Wallace, Thompson-Snipes, LuAnn, Baldini, Antonio, Illingworth, Elizabeth
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867300/
https://www.ncbi.nlm.nih.gov/pubmed/20439995
http://dx.doi.org/10.1083/jcb.200912037