Cargando…

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia

Invasive cancer cells are believed to breach the basement membrane (BM) using specialized protrusions called invadopodia. We found that the crossing of a native BM is a three-stage process: invadopodia indeed form and perforate the BM, elongate into mature invadopodia, and then guide the cell toward...

Descripción completa

Detalles Bibliográficos
Autores principales: Schoumacher, Marie, Goldman, Robert D., Louvard, Daniel, Vignjevic, Danijela M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867303/
https://www.ncbi.nlm.nih.gov/pubmed/20421424
http://dx.doi.org/10.1083/jcb.200909113