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β-Arrestin–dependent activation of Ca(2+)/calmodulin kinase II after β(1)–adrenergic receptor stimulation
Ca(2+)/calmodulin kinase II (CaMKII) plays an important role in cardiac contractility and the development of heart failure. Although stimulation of β(1)–adrenergic receptors (ARs) leads to an increase in CaMKII activity, the molecular mechanism by which β(1)-ARs activate CaMKII is not completely und...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867304/ https://www.ncbi.nlm.nih.gov/pubmed/20421423 http://dx.doi.org/10.1083/jcb.200911047 |