Cargando…

β-Arrestin–dependent activation of Ca(2+)/calmodulin kinase II after β(1)–adrenergic receptor stimulation

Ca(2+)/calmodulin kinase II (CaMKII) plays an important role in cardiac contractility and the development of heart failure. Although stimulation of β(1)–adrenergic receptors (ARs) leads to an increase in CaMKII activity, the molecular mechanism by which β(1)-ARs activate CaMKII is not completely und...

Descripción completa

Detalles Bibliográficos
Autores principales: Mangmool, Supachoke, Shukla, Arun K., Rockman, Howard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867304/
https://www.ncbi.nlm.nih.gov/pubmed/20421423
http://dx.doi.org/10.1083/jcb.200911047

Ejemplares similares