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LET-99 inhibits lateral posterior pulling forces during asymmetric spindle elongation in C. elegans embryos

Cortical pulling on astral microtubules positions the mitotic spindle in response to PAR polarity cues and G protein signaling in many systems. In Caenorhabditis elegans single-cell embryos, posterior spindle displacement depends on Gα and its regulators GPR-1/2 and LIN-5. GPR-1/2 and LIN-5 are nece...

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Detalles Bibliográficos
Autores principales: Krueger, Lori E., Wu, Jui-Ching, Tsou, Meng-Fu Bryan, Rose, Lesilee S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867312/
https://www.ncbi.nlm.nih.gov/pubmed/20421425
http://dx.doi.org/10.1083/jcb.201001115