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LET-99 inhibits lateral posterior pulling forces during asymmetric spindle elongation in C. elegans embryos
Cortical pulling on astral microtubules positions the mitotic spindle in response to PAR polarity cues and G protein signaling in many systems. In Caenorhabditis elegans single-cell embryos, posterior spindle displacement depends on Gα and its regulators GPR-1/2 and LIN-5. GPR-1/2 and LIN-5 are nece...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867312/ https://www.ncbi.nlm.nih.gov/pubmed/20421425 http://dx.doi.org/10.1083/jcb.201001115 |