A Penalized Mixture Model Approach in Genotype/Phenotype Association Analysis for Quantitative Phenotypes

A mixture normal model has been developed to partition genotypes in predicting quantitative phenotypes. Its estimation and inference are performed through an EM algorithm. This approach can conduct simultaneous genotype clustering and hypothesis testing. It is a valuable method for predicting the di...

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Detalles Bibliográficos
Autores principales: Li, Lang, Borges, Silvana, Jason, Robarge D., Shen, Changyu, Desta, Zeruesenay, Flockhart, David
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867634/
https://www.ncbi.nlm.nih.gov/pubmed/20467479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867634/
https://www.ncbi.nlm.nih.gov/pubmed/20467479

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