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A Penalized Mixture Model Approach in Genotype/Phenotype Association Analysis for Quantitative Phenotypes
A mixture normal model has been developed to partition genotypes in predicting quantitative phenotypes. Its estimation and inference are performed through an EM algorithm. This approach can conduct simultaneous genotype clustering and hypothesis testing. It is a valuable method for predicting the di...
Autores principales: | Li, Lang, Borges, Silvana, Jason, Robarge D., Shen, Changyu, Desta, Zeruesenay, Flockhart, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867634/ https://www.ncbi.nlm.nih.gov/pubmed/20467479 |
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