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Regulation of PCNA polyubiquitination in human cells

BACKGROUND: The ubiquitin-based molecular switch dictating error free versus error prone repair has been conserved throughout eukaryotic evolution. A central component of this switch is the homotrimeric clamp PCNA, which is ubiquitinated in response to genotoxic stress allowing recovery of replicati...

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Detalles Bibliográficos
Autores principales:	Brun, Jan, Chiu, Roland K, Wouters, Bradly G, Gray, Douglas A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867771/ https://www.ncbi.nlm.nih.gov/pubmed/20353596 http://dx.doi.org/10.1186/1756-0500-3-85

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