Regulation of PCNA polyubiquitination in human cells

BACKGROUND: The ubiquitin-based molecular switch dictating error free versus error prone repair has been conserved throughout eukaryotic evolution. A central component of this switch is the homotrimeric clamp PCNA, which is ubiquitinated in response to genotoxic stress allowing recovery of replicati...

Descripción completa

Detalles Bibliográficos
Autores principales: Brun, Jan, Chiu, Roland K, Wouters, Bradly G, Gray, Douglas A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867771/
https://www.ncbi.nlm.nih.gov/pubmed/20353596
http://dx.doi.org/10.1186/1756-0500-3-85

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867771/
https://www.ncbi.nlm.nih.gov/pubmed/20353596
http://dx.doi.org/10.1186/1756-0500-3-85

Ejemplares similares