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TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1

Polyubiquitination of proliferating cell nuclear antigen (PCNA) regulates the error-free template-switching mechanism for the bypass of DNA lesions during DNA replication. PCNA polyubiquitination is critical for the maintenance of genomic integrity; however, the underlying mechanism is poorly unders...

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Detalles Bibliográficos
Autores principales: Kang, Hyun Je, Park, Hyun, Yoo, Eun Jin, Lee, Jun Ho, Choi, Soo Youn, Lee-Kwon, Whaseon, Lee, Kyoo-young, Hur, Jin-Hoe, Seo, Jeong Kon, Ra, Jae Sun, Lee, Eun-A., Myung, Kyungjae, Kwon, Hyug Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677787/
https://www.ncbi.nlm.nih.gov/pubmed/31376680
http://dx.doi.org/10.1016/j.isci.2019.07.021