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Hidden reach of the micromanagers

Small interfering RNAs can trigger unintended, microRNA-like off-target effects, but the impact of these effects on functional studies has been controversial. A recent study in BMC Genomics shows that microRNA-like effects can predominate among the 'hits' of functional genomics screens. Se...

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Detalles Bibliográficos
Autores principales: Linsley, Peter S, Jackson, Aimee L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867781/
https://www.ncbi.nlm.nih.gov/pubmed/20529236
http://dx.doi.org/10.1186/1741-7007-8-53