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Autotaxin expression and its connection with the TNF-alpha-NF-κB axis in human hepatocellular carcinoma

BACKGROUND: Autotaxin (ATX) is an extracellular lysophospholipase D that generates lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC). Both ATX and LPA have been shown to be involved in many cancers. However, the functional role of ATX and the regulation of ATX expression in human hepato...

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Detalles Bibliográficos
Autores principales: Wu, Jian-Min, Xu, Yan, Skill, Nicholas J, Sheng, Hongmiao, Zhao, Zhenwen, Yu, Menggang, Saxena, Romil, Maluccio, Mary A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867819/
https://www.ncbi.nlm.nih.gov/pubmed/20356387
http://dx.doi.org/10.1186/1476-4598-9-71