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Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes
BACKGROUND: New drug targets are urgently needed for parasites of socio-economic importance. Genes that are essential for parasite survival are highly desirable targets, but information on these genes is lacking, as gene knockouts or knockdowns are difficult to perform in many species of parasites....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867826/ https://www.ncbi.nlm.nih.gov/pubmed/20361874 http://dx.doi.org/10.1186/1471-2164-11-222 |