Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels

BACKGROUND: Plasmodium falciparum, the causative agent of severe human malaria, has evolved to become resistant to previously successful antimalarial chemotherapies, most notably chloroquine and the antifolates. The prevalence of resistant strains has necessitated the discovery and development of ne...

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Detalles Bibliográficos
Autores principales: Becker, John VW, Mtwisha, Linda, Crampton, Bridget G, Stoychev, Stoyan, van Brummelen, Anna C, Reeksting, Shaun, Louw, Abraham I, Birkholtz, Lyn-Marie, Mancama, Dalu T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867828/
https://www.ncbi.nlm.nih.gov/pubmed/20385001
http://dx.doi.org/10.1186/1471-2164-11-235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867828/
https://www.ncbi.nlm.nih.gov/pubmed/20385001
http://dx.doi.org/10.1186/1471-2164-11-235

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