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Adverse events, bone mineral density and discontinuation associated with generic alendronate among postmenopausal women previously tolerant of brand alendronate: a retrospective cohort study

BACKGROUND: A rise in gastrointestinal (GI) adverse events (AEs) and a decline in bone mineral density (BMD) was observed in patients previously tolerant to brand alendronate shortly after generic versions were introduced in July 2005 to the Canadian market. The objective of our study was to quantif...

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Detalles Bibliográficos
Autores principales: Grima, Daniel T, Papaioannou, Alexandra, Airia, Parisa, Ioannidis, George, Adachi, Jonathan D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867835/
https://www.ncbi.nlm.nih.gov/pubmed/20388226
http://dx.doi.org/10.1186/1471-2474-11-68