Computational Identification of Uncharacterized Cruzain Binding Sites

Chagas disease, caused by the unicellular parasite Trypanosoma cruzi, claims 50,000 lives annually and is the leading cause of infectious myocarditis in the world. As current antichagastic therapies like nifurtimox and benznidazole are highly toxic, ineffective at parasite eradication, and subject t...

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Detalles Bibliográficos
Autores principales: Durrant, Jacob D., Keränen, Henrik, Wilson, Benjamin A., McCammon, J. Andrew
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867933/
https://www.ncbi.nlm.nih.gov/pubmed/20485483
http://dx.doi.org/10.1371/journal.pntd.0000676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867933/
https://www.ncbi.nlm.nih.gov/pubmed/20485483
http://dx.doi.org/10.1371/journal.pntd.0000676

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