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A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

Mammalian genomes are pervasively transcribed outside mapped protein-coding genes. One class of extragenic transcription products is represented by long non-coding RNAs (lncRNAs), some of which result from Pol_II transcription of bona-fide RNA genes. Whether all lncRNAs described insofar are product...

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Detalles Bibliográficos
Autores principales: De Santa, Francesca, Barozzi, Iros, Mietton, Flore, Ghisletti, Serena, Polletti, Sara, Tusi, Betsabeh Khoramian, Muller, Heiko, Ragoussis, Jiannis, Wei, Chia-Lin, Natoli, Gioacchino
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867938/
https://www.ncbi.nlm.nih.gov/pubmed/20485488
http://dx.doi.org/10.1371/journal.pbio.1000384