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High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function
BACKGROUND: Cultured spinal motor neurons are a valuable tool to study basic mechanisms of development, axon growth and pathfinding, and, importantly, to analyze the pathomechanisms underlying motor neuron diseases. However, the application of this cell culture model is limited by the lack of effici...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867961/ https://www.ncbi.nlm.nih.gov/pubmed/20406490 http://dx.doi.org/10.1186/1750-1326-5-17 |