Significant Impact of Sequence Variations in the Nucleoprotein on CD8 T Cell-Mediated Cross-Protection against Influenza A Virus Infections

BACKGROUND: Memory CD8 T cells to influenza A viruses are widely detectable in healthy human subjects and broadly cross-reactive for serologically distinct influenza A virus subtypes. However, it is not clear to what extent such pre-existing cellular immunity can provide cross-subtype protection aga...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Weimin, Liu, Feng, Dong, Libo, Lu, Xiuhua, Hancock, Kathy, Reinherz, Ellis L., Katz, Jacqueline M., Sambhara, Suryaprakash
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868023/
https://www.ncbi.nlm.nih.gov/pubmed/20485501
http://dx.doi.org/10.1371/journal.pone.0010583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868023/
https://www.ncbi.nlm.nih.gov/pubmed/20485501
http://dx.doi.org/10.1371/journal.pone.0010583

Ejemplares similares