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Ultrathin nucleoporin phenylalanine–glycine repeat films and their interaction with nuclear transport receptors

Nuclear pore complexes (NPCs) are highly selective gates that mediate the exchange of all proteins and nucleic acids between the cytoplasm and the nucleus. Their selectivity relies on a supramolecular assembly of natively unfolded nucleoporin domains containing phenylalanine–glycine (FG)-rich repeat...

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Detalles Bibliográficos
Autores principales: Eisele, Nico B, Frey, Steffen, Piehler, Jacob, Görlich, Dirk, Richter, Ralf P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868541/
https://www.ncbi.nlm.nih.gov/pubmed/20379223
http://dx.doi.org/10.1038/embor.2010.34