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Interactions of unconjugated bilirubin with vesicles, cyclodextrins and micelles: New modeling and the role of high pKa values

BACKGROUND: Unconjugated bilirubin (UCB) is an unstable substance with very low aqueous solubility. Its aqueous pKa values affect many of its interactions, particularly their pH-dependence. A companion paper shows that only our prior solvent partition studies, leading to pKa values of 8.12 and 8.44,...

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Detalles Bibliográficos
Autores principales: Mukerjee, Pasupati, Ostrow, J Donald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868783/
https://www.ncbi.nlm.nih.gov/pubmed/20350304
http://dx.doi.org/10.1186/1471-2091-11-16