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Human macrophage foam cells degrade atherosclerotic plaques through cathepsin K mediated processes

BACKGROUND: Proteolytic degradation of Type I Collagen by proteases may play an important role in remodeling of atherosclerotic plaques, contributing to increased risk of plaque rupture. The aim of the current study was to investigate whether human macrophage foam cells degrade the extracellular mat...

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Detalles Bibliográficos
Autores principales: Barascuk, Natasha, Skjøt-Arkil, Helene, Register, Thomas C, Larsen, Lise, Byrjalsen, Inger, Christiansen, Claus, Karsdal, Morten A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868786/
https://www.ncbi.nlm.nih.gov/pubmed/20409295
http://dx.doi.org/10.1186/1471-2261-10-19