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Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma

BACKGROUND: Tumor cell proliferation is a predictor of survival in cutaneous melanoma. The aim of the present study was to evaluate the prognostic impact of mitotic count, Ki-67 expression and novel proliferation markers phosphohistone H3 (PHH3), minichromosome maintenance protein 4 (MCM4) and mitos...

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Detalles Bibliográficos
Autores principales: Ladstein, Rita G, Bachmann, Ingeborg M, Straume, Oddbjørn, Akslen, Lars A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868809/
https://www.ncbi.nlm.nih.gov/pubmed/20398247
http://dx.doi.org/10.1186/1471-2407-10-140