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Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma
BACKGROUND: Tumor cell proliferation is a predictor of survival in cutaneous melanoma. The aim of the present study was to evaluate the prognostic impact of mitotic count, Ki-67 expression and novel proliferation markers phosphohistone H3 (PHH3), minichromosome maintenance protein 4 (MCM4) and mitos...
Autores principales: | Ladstein, Rita G, Bachmann, Ingeborg M, Straume, Oddbjørn, Akslen, Lars A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868809/ https://www.ncbi.nlm.nih.gov/pubmed/20398247 http://dx.doi.org/10.1186/1471-2407-10-140 |
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