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Tumor morphological evolution: directed migration and gain and loss of the self-metastatic phenotype

BACKGROUND: Aside from the stepwise genetic alterations known to underlie cancer cell creation, the microenvironment is known to profoundly influence subsequent tumor development, morphology and metastasis. Invasive cluster formation has been assumed to be dependent on directed migration and a heter...

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Detalles Bibliográficos
Autores principales: Enderling, Heiko, Hlatky, Lynn, Hahnfeldt, Philip
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868833/
https://www.ncbi.nlm.nih.gov/pubmed/20406441
http://dx.doi.org/10.1186/1745-6150-5-23