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Cancer Testis Antigen Vaccination Affords Long-Term Protection in a Murine Model of Ovarian Cancer

Sperm protein (Sp17) is an attractive target for ovarian cancer (OC) vaccines because of its over-expression in primary as well as in metastatic lesions, at all stages of the disease. Our studies suggest that a Sp17-based vaccine can induce an enduring defense against OC development in C57BL/6 mice...

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Detalles Bibliográficos
Autores principales: Chiriva-Internati, Maurizio, Yu, Yuefei, Mirandola, Leonardo, Jenkins, Marjorie R., Chapman, Caroline, Cannon, Martin, Cobos, Everardo, Kast, W. Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868870/
https://www.ncbi.nlm.nih.gov/pubmed/20485677
http://dx.doi.org/10.1371/journal.pone.0010471