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Cancer Testis Antigen Vaccination Affords Long-Term Protection in a Murine Model of Ovarian Cancer
Sperm protein (Sp17) is an attractive target for ovarian cancer (OC) vaccines because of its over-expression in primary as well as in metastatic lesions, at all stages of the disease. Our studies suggest that a Sp17-based vaccine can induce an enduring defense against OC development in C57BL/6 mice...
Autores principales: | Chiriva-Internati, Maurizio, Yu, Yuefei, Mirandola, Leonardo, Jenkins, Marjorie R., Chapman, Caroline, Cannon, Martin, Cobos, Everardo, Kast, W. Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868870/ https://www.ncbi.nlm.nih.gov/pubmed/20485677 http://dx.doi.org/10.1371/journal.pone.0010471 |
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