Investigating the Epigenetic Effects of a Prototype Smoke-Derived Carcinogen in Human Cells

Global loss of DNA methylation and locus/gene-specific gain of DNA methylation are two distinct hallmarks of carcinogenesis. Aberrant DNA methylation is implicated in smoking-related lung cancer. In this study, we have comprehensively investigated the modulation of DNA methylation consequent to chro...

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Detalles Bibliográficos
Autores principales: Tommasi, Stella, Kim, Sang-in, Zhong, Xueyan, Wu, Xiwei, Pfeifer, Gerd P., Besaratinia, Ahmad
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868871/
https://www.ncbi.nlm.nih.gov/pubmed/20485678
http://dx.doi.org/10.1371/journal.pone.0010594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868871/
https://www.ncbi.nlm.nih.gov/pubmed/20485678
http://dx.doi.org/10.1371/journal.pone.0010594

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