Cargando…

JC Virus Small t Antigen Binds Phosphatase PP2A and Rb Family Proteins and Is Required for Efficient Viral DNA Replication Activity

BACKGROUND: The human polyomavirus, JC virus (JCV) produces five tumor proteins encoded by transcripts alternatively spliced from one precursor messenger RNA. Significant attention has been given to replication and transforming activities of JCV's large tumor antigen (TAg) and three T′ proteins...

Descripción completa

Detalles Bibliográficos
Autores principales: Bollag, Brigitte, Hofstetter, Catherine A., Reviriego-Mendoza, Marta M., Frisque, Richard J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868895/
https://www.ncbi.nlm.nih.gov/pubmed/20485545
http://dx.doi.org/10.1371/journal.pone.0010606