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Interaction between Thymidylate Synthase and Its Cognate mRNA in Zebrafish Embryos

Thymidylate synthase (TS), which catalyzes the de novo synthesis of dUMP, is an important target for cancer therapy. In this report, the effects of 5-fluorouracil (5-FU) and ZD1694 on the regulation of TS gene expression were evaluated in zebrafish embryos. Our results revealed that the expression o...

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Detalles Bibliográficos
Autores principales: Zhang, Yuyan, Yang, Shaoli, Liu, Ming, Song, Chunxia, Wu, Ning, Ling, Peixue, Chu, Edward, Lin, Xiukun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868900/
https://www.ncbi.nlm.nih.gov/pubmed/20485548
http://dx.doi.org/10.1371/journal.pone.0010618