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Interaction between Thymidylate Synthase and Its Cognate mRNA in Zebrafish Embryos
Thymidylate synthase (TS), which catalyzes the de novo synthesis of dUMP, is an important target for cancer therapy. In this report, the effects of 5-fluorouracil (5-FU) and ZD1694 on the regulation of TS gene expression were evaluated in zebrafish embryos. Our results revealed that the expression o...
Autores principales: | Zhang, Yuyan, Yang, Shaoli, Liu, Ming, Song, Chunxia, Wu, Ning, Ling, Peixue, Chu, Edward, Lin, Xiukun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868900/ https://www.ncbi.nlm.nih.gov/pubmed/20485548 http://dx.doi.org/10.1371/journal.pone.0010618 |
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