H2AX phosphorylation screen of cells from radiosensitive cancer patients reveals a novel DNA double-strand break repair cellular phenotype

BACKGROUND: About 1–5% of cancer patients suffer from significant normal tissue reactions as a result of radiotherapy (RT). It is not possible at this time to predict how most patients’ normal tissues will respond to RT. DNA repair dysfunction is implicated in sensitivity to RT particularly in genes...

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Detalles Bibliográficos
Autores principales: Vasireddy, R S, Sprung, C N, Cempaka, N L, Chao, M, McKay, M J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869166/
https://www.ncbi.nlm.nih.gov/pubmed/20461094
http://dx.doi.org/10.1038/sj.bjc.6605666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869166/
https://www.ncbi.nlm.nih.gov/pubmed/20461094
http://dx.doi.org/10.1038/sj.bjc.6605666

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