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QSAR Studies on Andrographolide Derivatives as α-Glucosidase Inhibitors

Andrographolide derivatives were shown to inhibit α-glucosidase. To investigate the relationship between activities and structures of andrographolide derivatives, a training set was chosen from 25 andrographolide derivatives by the principal component analysis (PCA) method, and a quantitative struct...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Huang, Sichao, Luo, Haibin, Li, Guoji, Bao, Jiaolin, Cai, Shaohui, Wang, Yuqiang
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869241/
https://www.ncbi.nlm.nih.gov/pubmed/20479989
http://dx.doi.org/10.3390/ijms11030880