Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens

[Image: see text] Described is an efficient heterologous expression system for Sulfolobus solfataricus ADH-10 (Alcohol Dehydrogenase isozyme 10) and its use in the dynamic reductive kinetic resolution (DYRKR) of 2-arylpropanal (Profen-type) substrates. Importantly, among the 12 aldehydes tested, a g...

Descripción completa

Detalles Bibliográficos
Autores principales: Friest, Jacob A., Maezato, Yukari, Broussy, Sylvain, Blum, Paul, Berkowitz, David B.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869291/
https://www.ncbi.nlm.nih.gov/pubmed/20377222
http://dx.doi.org/10.1021/ja910778p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869291/
https://www.ncbi.nlm.nih.gov/pubmed/20377222
http://dx.doi.org/10.1021/ja910778p

Ejemplares similares