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Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens
[Image: see text] Described is an efficient heterologous expression system for Sulfolobus solfataricus ADH-10 (Alcohol Dehydrogenase isozyme 10) and its use in the dynamic reductive kinetic resolution (DYRKR) of 2-arylpropanal (Profen-type) substrates. Importantly, among the 12 aldehydes tested, a g...
Autores principales: | Friest, Jacob A., Maezato, Yukari, Broussy, Sylvain, Blum, Paul, Berkowitz, David B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869291/ https://www.ncbi.nlm.nih.gov/pubmed/20377222 http://dx.doi.org/10.1021/ja910778p |
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