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mRNA Export from Mammalian Cell Nuclei Is Dependent on GANP

Bulk nuclear export of messenger ribonucleoproteins (mRNPs) through nuclear pore complexes (NPCs) is mediated by NXF1. It binds mRNPs through adaptor proteins such as ALY [1, 2] and SR splicing factors [3] and mediates translocation through the central NPC transport channel via transient interaction...

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Detalles Bibliográficos
Autores principales: Wickramasinghe, Vihandha O., McMurtrie, Paul I.A., Mills, Anthony D., Takei, Yoshinori, Penrhyn-Lowe, Sue, Amagase, Yoko, Main, Sarah, Marr, Jackie, Stewart, Murray, Laskey, Ronald A.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869303/
https://www.ncbi.nlm.nih.gov/pubmed/20005110
http://dx.doi.org/10.1016/j.cub.2009.10.078