Characterization of Oxidative Guanine Damage and Repair in Mammalian Telomeres

8-oxo-7,8-dihydroguanine (8-oxoG) and 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) are among the most common oxidative DNA lesions and are substrates for 8-oxoguanine DNA glycosylase (OGG1)–initiated DNA base excision repair (BER). Mammalian telomeres consist of triple guanine repeats and are...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhilong, Rhee, David B., Lu, Jian, Bohr, Christina T., Zhou, Fang, Vallabhaneni, Haritha, de Souza-Pinto, Nadja C., Liu, Yie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869316/
https://www.ncbi.nlm.nih.gov/pubmed/20485567
http://dx.doi.org/10.1371/journal.pgen.1000951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869316/
https://www.ncbi.nlm.nih.gov/pubmed/20485567
http://dx.doi.org/10.1371/journal.pgen.1000951

Ejemplares similares