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Using Canonical Correlation Analysis to Discover Genetic Regulatory Variants

BACKGROUND: Discovering genetic associations between genetic markers and gene expression levels can provide insight into gene regulation and, potentially, mechanisms of disease. Such analyses typically involve a linkage or association analysis in which expression data are used as phenotypes. This ap...

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Detalles Bibliográficos
Autores principales: Naylor, Melissa G., Lin, Xihong, Weiss, Scott T., Raby, Benjamin A., Lange, Christoph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869348/
https://www.ncbi.nlm.nih.gov/pubmed/20485529
http://dx.doi.org/10.1371/journal.pone.0010395