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Effective Melanoma Immunotherapy in Mice by the Skin-Depigmenting Agent Monobenzone and the Adjuvants Imiquimod and CpG

BACKGROUND: Presently melanoma still lacks adequate treatment options for metastatic disease. While melanoma is exceptionally challenging to standard regimens, it is suited for treatment with immunotherapy based on its immunogenicity. Since treatment-related skin depigmentation is considered a favou...

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Detalles Bibliográficos
Autores principales: van den Boorn, Jasper G., Konijnenberg, Debby, Tjin, Esther P. M., Picavet, Daisy I., Meeuwenoord, Nico J., Filippov, Dmitri V., van der Veen, J. P. Wietze, Bos, Jan D., Melief, Cornelis J. M., Luiten, Rosalie M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869359/
https://www.ncbi.nlm.nih.gov/pubmed/20498710
http://dx.doi.org/10.1371/journal.pone.0010626