Superoxide Dismutase 1 and tgSOD1(G93A) Mouse Spinal Cord Seed Fibrils, Suggesting a Propagative Cell Death Mechanism in Amyotrophic Lateral Sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that specifically affects motor neurons and leads to a progressive and ultimately fatal loss of function, resulting in death typically within 3 to 5 years of diagnosis. The disease starts with a focal centre of weakness,...

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Detalles Bibliográficos
Autores principales: Chia, Ruth, Tattum, M. Howard, Jones, Samantha, Collinge, John, Fisher, Elizabeth M. C., Jackson, Graham S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869360/
https://www.ncbi.nlm.nih.gov/pubmed/20498711
http://dx.doi.org/10.1371/journal.pone.0010627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869360/
https://www.ncbi.nlm.nih.gov/pubmed/20498711
http://dx.doi.org/10.1371/journal.pone.0010627

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