Low Dosage of Histone H4 Leads to Growth Defects and Morphological Changes in Candida albicans

Chromatin function depends on adequate histone stoichiometry. Alterations in histone dosage affect transcription and chromosome segregation, leading to growth defects and aneuploidies. In the fungal pathogen Candida albicans, aneuploidy formation is associated with antifungal resistance and pathogen...

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Detalles Bibliográficos
Autores principales: Zacchi, Lucia F., Selmecki, Anna M., Berman, Judith, Davis, Dana A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869362/
https://www.ncbi.nlm.nih.gov/pubmed/20498713
http://dx.doi.org/10.1371/journal.pone.0010629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869362/
https://www.ncbi.nlm.nih.gov/pubmed/20498713
http://dx.doi.org/10.1371/journal.pone.0010629

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