Low Dosage of Histone H4 Leads to Growth Defects and Morphological Changes in Candida albicans

Chromatin function depends on adequate histone stoichiometry. Alterations in histone dosage affect transcription and chromosome segregation, leading to growth defects and aneuploidies. In the fungal pathogen Candida albicans, aneuploidy formation is associated with antifungal resistance and pathogen...

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Bibliografische gegevens
Hoofdauteurs: Zacchi, Lucia F., Selmecki, Anna M., Berman, Judith, Davis, Dana A.
Formaat: Texto
Taal:English
Gepubliceerd in: Public Library of Science 2010
Onderwerpen:
Research Article
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869362/
https://www.ncbi.nlm.nih.gov/pubmed/20498713
http://dx.doi.org/10.1371/journal.pone.0010629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869362/
https://www.ncbi.nlm.nih.gov/pubmed/20498713
http://dx.doi.org/10.1371/journal.pone.0010629

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